产品货号：
Z35575
中文名称：
NEDD4抗体
英文名称：
Anti-NEDD4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NEDD4 Antibody |
| 指标别名 | KIAA0093;NEDD 4;NEDD4;NEDD4 1;RPF1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | NEDD4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human NEDD4 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Involved in the pathway leading to the degradation of VEGFR-2/KDFR,independently of its ubiquitin-ligase activity. |
| 实际分子量 | 105～150KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 ubiquitin-protein ligase NEDD4,also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4),is an enzyme that in humans is encoded by the NEDD4 gene.This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation.The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and,a C-terminal HECT ubiquitin ligase catalytic domain.It plays critical role in the regulation of a number of membrane receptors,endocytic machinery components and the tumor suppressor PTEN. |
| Uniprot ID | P46934 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：NEDD4抗体，NEDD4单抗，Anti-NEDD4 Antibody